研究方向:
本人研究方向主要集中在磷脂与囊泡运输。将以拟南芥、水稻、大豆等模式植物为材料,利用先进的显微镜技术、生物化学手段、透射电子显微镜、转盘共聚焦等系统研究磷脂调控囊泡运输过程、参与植物生长发育和抗逆以及根瘤发生直接的关系。
另一方向是磷脂与细胞自噬。细胞自噬与植物抗逆密切相关。最近几年,植物的细胞自噬研究逐渐加快,我们期望通过研究深入了解磷脂是如何调控细胞自噬的,为今后农作物遗传改良即创制抗逆的作物新品种奠定基础。
承担项目:
威尼斯144777cm高层次人才引进启动基金, 100万
江苏省青年基金:磷脂酰肌醇-4-磷酸(PtdIns4P)应答生长素信号和调控植物根生长的分子机制研究,20万 (BK20200555)
国家自然科学基金青年基金,32100553,磷脂酰肌醇-4-磷酸调控PIN2囊泡运输响应生长素信号的分子机制,2022.01-2024.12,30万元,在研,主持。
招生方向:
09 (全日制)植物逆境生理与分子生物学
发表论文(*,通讯作者)
1、Lin F*, Zheng J, Xie Y, Jing W, Zhang Q, Zhang W*. (2022). Emerging roles of phosphoinositide-associated membrane trafficking in plant stress responses [published online ahead of print]. Journal of genetics and genomics. 2022;S1673-8527(22)00154-0. (IF,5.723)
2、Song, P., Xu, H., Zhang, J., Chen, H., Li, L., Qu, Y., Lin, F*., and Zhang, Q*. (2021). Functional analysis of indole 3-hexanoic acid as a novel auxin from Arabidopsis thaliana. Planta 254, 69. (IF,4.11)
3、Song, T., Shi, Y., Shen, L., Cao, C., Shen, Y., Jing, W., Tian, Q., Lin, F., Li, W., & Zhang, W. (2021). An endoplasmic reticulum-localized cytochrome b5 regulates high-affinity K+ transport in response to salt stress in rice. Proceedings of the National Academy of Sciences of the United States of America 118(50), e2114347118.(IF,11.205)
4、Jing, G., Tang, D., Yao, Y., Su, Y., Shen, Y., Bai, Y., Jing, W., Zhang, Q., Lin, F*., Guo, D*., et al. (2021). Seed specifically over-expressing DGAT2A enhances oil and linoleic acid contents in soybean seeds. Biochemical and Biophysical Research Communications 568, 143-150. (IF,3.575)
5、Lin F, Krishnamoorthy P, Schubert V, Hause G, Heilmann M, Heilmann I (2019). A dual role for PI4Kβ in endocytosis and phragmoplast dynamics during plant somatic cytokinesis. EMBO Journal 38, e100303 (IF, 10.557)
6、Lin F, Qu Y, Zhang Q (2014) Phospholipids: molecules regulating cytoskeletal organization in plant abiotic stress tolerance. Plant Signal Behav 9(3):e28337.
7、Gerth K, Lin F, Daamen F, Menzel W, Heinrich F, Heilmann, M. (2017a). Arabidopsis phosphatidylinositol 4-phosphate 5-kinase 2 contains a functional nuclear localization sequence and interacts with alpha-importins. The Plant Journal 92, 862-878.(IF, 5.78)
8、Gerth K, Lin F, Menzel W, Krishnamoorthy P, Stenzel I, Heilmann M, Heilmann, I. (2017b). Guilt by Association: A Phenotype-Based View of the Plant Phosphoinositide Network. Annual Review of Plant Biology 68, 349-374. (IF, 18.71)
9、Zhang Q, Lin F, Mao T, Nie J, Yan M, Yuan M, Zhang W (2012) Phosphatidic acid regulates microtubule organization by interacting with MAP65-1 in response to salt stress in Arabidopsis. Plant Cell 24(11):4555-76. (IF, 8.23)
10、Jiang Y, Wu K, Lin F, Qu Y, Liu X, Zhang Q (2014) Phosphatidic acid integrates calcium signaling and microtubule dynamics into regulating ABA-induced stomatal closure in Arabidopsis. Planta 239(3):565-75.(IF, 3.25)